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2001 1
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2005 2
2006 3
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2010 2
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2012 4
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Page 1
BAFF and APRIL counterregulate susceptibility to inflammation-induced preterm birth.
Doll JR, Moreno-Fernandez ME, Stankiewicz TE, Wayland JL, Wilburn A, Weinhaus B, Chougnet CA, Giordano D, Cappelletti M, Presicce P, Kallapur SG, Salomonis N, Tilburgs T, Divanovic S. Doll JR, et al. Cell Rep. 2023 Apr 25;42(4):112352. doi: 10.1016/j.celrep.2023.112352. Epub 2023 Apr 5. Cell Rep. 2023. PMID: 37027297 Free PMC article.
Here, via utility of genetically modified mice, we report that BAFF promotes inflammatory responsiveness and increases susceptibility to inflammation-induced preterm birth (PTB). In contrast, we show that the closely related A proliferation-inducing ligand (APRIL) decrease …
Here, via utility of genetically modified mice, we report that BAFF promotes inflammatory responsiveness and increases susceptibility to …
BAFF AND APRIL: a tutorial on B cell survival.
Mackay F, Schneider P, Rennert P, Browning J. Mackay F, et al. Annu Rev Immunol. 2003;21:231-64. doi: 10.1146/annurev.immunol.21.120601.141152. Epub 2001 Dec 19. Annu Rev Immunol. 2003. PMID: 12427767 Review.
TNFSF13 Is a Novel Onco-Inflammatory Marker and Correlates With Immune Infiltration in Gliomas.
Chen R, Wang X, Dai Z, Wang Z, Wu W, Hu Z, Zhang X, Liu Z, Zhang H, Cheng Q. Chen R, et al. Front Immunol. 2021 Oct 12;12:713757. doi: 10.3389/fimmu.2021.713757. eCollection 2021. Front Immunol. 2021. PMID: 34712225 Free PMC article.
In high TNFSF13 gliomas, somatic mutation was proved to correlate with amplification of EGFR and deletion of CDKN2A; while mutation of IDH1 was more frequently observed in low TNFSF13 group. ...Further, TNFSF13 was found to be involved in immunosuppression vi …
In high TNFSF13 gliomas, somatic mutation was proved to correlate with amplification of EGFR and deletion of CDKN2A; while mutation o …
Exosome Derived from Mesenchymal Stem Cells Alleviates Hypertrophic Scar by Inhibiting the Fibroblasts via TNFSF-13/HSPG2 Signaling Pathway.
Zhang H, Zang C, Zhao W, Zhang L, Liu R, Feng Z, Wu J, Cui R. Zhang H, et al. Int J Nanomedicine. 2023 Nov 28;18:7047-7063. doi: 10.2147/IJN.S433510. eCollection 2023. Int J Nanomedicine. 2023. PMID: 38046235 Free PMC article.
HSF were treated with recombinant TNFSF13 protein and TNFSF13 siRNAs to probe the effect of TNFSF13 on the activity of HSF. ...Recombinant TNFSF13 protein increased cell viability, proliferation, migration, fibrosis, inflammation, and the bindin …
HSF were treated with recombinant TNFSF13 protein and TNFSF13 siRNAs to probe the effect of TNFSF13 on the activity of …
APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans.
Tsiantoulas D, Eslami M, Obermayer G, Clement M, Smeets D, Mayer FJ, Kiss MG, Enders L, Weißer J, Göderle L, Lambert J, Frommlet F, Mueller A, Hendrikx T, Ozsvar-Kozma M, Porsch F, Willen L, Afonyushkin T, Murphy JE, Fogelstrand P, Donzé O, Pasterkamp G, Hoke M, Kubicek S, Jørgensen HF, Danchin N, Simon T, Scharnagl H, März W, Borén J, Hess H, Mallat Z, Schneider P, Binder CJ. Tsiantoulas D, et al. Nature. 2021 Sep;597(7874):92-96. doi: 10.1038/s41586-021-03818-3. Epub 2021 Aug 25. Nature. 2021. PMID: 34433968
The formation of atherosclerotic plaques is initiated when low-density lipoproteins bind to heparan-sulfate proteoglycans (HSPGs)(2) and become trapped in the subendothelial space of large and medium size arteries, which leads to chronic inflammation and remodelling of the …
The formation of atherosclerotic plaques is initiated when low-density lipoproteins bind to heparan-sulfate proteoglycans (HSPGs)(2) and bec …
The contribution of a proliferation-inducing ligand (APRIL) and other TNF superfamily members in pathogenesis and progression of IgA nephropathy.
Yeo SC, Barratt J. Yeo SC, et al. Clin Kidney J. 2023 Dec 4;16(Suppl 2):ii9-ii18. doi: 10.1093/ckj/sfad200. eCollection 2023 Dec. Clin Kidney J. 2023. PMID: 38053976 Free PMC article. Review.
Conversely, anti-APRIL therapy reduces pathogenic Gd-IgA1 and IgA immune complex formation and ameliorates the severity of kidney inflammation and injury. Genome-wide association studies in IgAN have identified TNFSF13 and TNFRSF13B, a cytokine ligand-receptor gene …
Conversely, anti-APRIL therapy reduces pathogenic Gd-IgA1 and IgA immune complex formation and ameliorates the severity of kidney inflamm …
Relationships between inflammation- and immunity-related transcript abundance in the rumen and jejunum of beef steers with divergent average daily gain.
Reynolds JG, Foote AP, Freetly HC, Oliver WT, Lindholm-Perry AK. Reynolds JG, et al. Anim Genet. 2017 Aug;48(4):447-449. doi: 10.1111/age.12546. Epub 2017 Feb 21. Anim Genet. 2017. PMID: 28220507
However, in the rumen, two chemokine genes (CCL11, CXCL5) and one receptor gene (IL10RA) were detected as differentially expressed (P < 0.05). The genes IL1A, BMP2, CXCL12 and TNFSF13 also displayed trends for differential expression (P < 0.10). ...

However, in the rumen, two chemokine genes (CCL11, CXCL5) and one receptor gene (IL10RA) were detected as differentially expressed (P < 0

…
Increased cortical lesion load and intrathecal inflammation is associated with oligoclonal bands in multiple sclerosis patients: a combined CSF and MRI study.
Farina G, Magliozzi R, Pitteri M, Reynolds R, Rossi S, Gajofatto A, Benedetti MD, Facchiano F, Monaco S, Calabrese M. Farina G, et al. J Neuroinflammation. 2017 Feb 21;14(1):40. doi: 10.1186/s12974-017-0812-y. J Neuroinflammation. 2017. PMID: 28222766 Free PMC article.
BACKGROUND: Although IgG oligoclonal bands (OCBs) in the cerebrospinal fluid (CSF) are a frequent phenomenon in multiple sclerosis (MS) patients, their relationship with grey matter lesions, intrathecal/meningeal inflammation and clinical evolution has not been clarified y …
BACKGROUND: Although IgG oligoclonal bands (OCBs) in the cerebrospinal fluid (CSF) are a frequent phenomenon in multiple sclerosis (MS) pati …
Rich oleocanthal and oleacein extra virgin olive oil and inflammatory and antioxidant status in people with obesity and prediabetes. The APRIL study: A randomised, controlled crossover study.
Ruiz-García I, Ortíz-Flores R, Badía R, García-Borrego A, García-Fernández M, Lara E, Martín-Montañez E, García-Serrano S, Valdés S, Gonzalo M, Tapia-Guerrero MJ, Fernández-García JC, Sánchez-García A, Muñoz-Cobos F, Calderón-Cid M, El-Bekay R, Covas MI, Rojo-Martínez G, Olveira G, Romero-Zerbo SY, Bermúdez-Silva FJ. Ruiz-García I, et al. Clin Nutr. 2023 Aug;42(8):1389-1398. doi: 10.1016/j.clnu.2023.06.027. Epub 2023 Jun 28. Clin Nutr. 2023. PMID: 37421852 Free article. Clinical Trial.
The role of the BAFF/APRIL system on T cell function.
Mackay F, Leung H. Mackay F, et al. Semin Immunol. 2006 Oct;18(5):284-9. doi: 10.1016/j.smim.2006.04.005. Epub 2006 Aug 22. Semin Immunol. 2006. PMID: 16931039 Review.
BAFF over-expression in transgenic (Tg) mice enhances T helper 1 (Thl)-driven delayed-type hypersensitivity (DTH), but inhibits T helper 2 (Th2) cell-mediated allergic airway inflammation in mice. Some of these effects are also dependent on BAFF-induced modification of the …
BAFF over-expression in transgenic (Tg) mice enhances T helper 1 (Thl)-driven delayed-type hypersensitivity (DTH), but inhibits T helper 2 ( …
52 results